Profile
Education and Training
Post-Doctoral Training Department of Psychiatry & Behavioral Neuroscience, The University of Chicago, 2007.11-2010.08
B.S.    East China Normal University (ECNU), Biochemistry, 1998-2002.
Ph.D.  Fudan University, Genetics, 2002-2007.

 

Selected Publications
1.Dandan Zhang, Yudong Qian, Nirmala Akula, Ney Alliey-Rodriguez, Jinsong Tang, The Bipolar Genome Study, Elliot S. Gershon, Chunyu Liu. Accuracy of CNV Detection from GWAS Data. PLoS One. 2011 Jan 13;6(1):e14511.
 
2. Dandan Zhang*, Lijun Cheng*, Judith A Badner, Chao Chen, Qi Chen, Wei Luo, Margot
Redman, David W Craig, Elliot S Gershon, Chunyu Liu. Genetic control of individual differences in gene-specific methylation in human. Am J Hum Genet. 2010, 86(3):411-9 (*equal contribution authors)
 
3. Dandan Zhang, Lijun Cheng, David W Craig, Margot Redman, Chunyu Liu. Cerebellar telomere length and psychiatric disorders. Behav Genet. 2010 40(2):250-4.
 
4. Dandan Zhang, Lijun Cheng, Yudong Qian, Ney Alliey-Rodriguez, et al. Singleton Deletions Throughout the Genome Increase Risk of Bipolar Disorder. Mol Psychiatry. 2009 14(4):376-80.
 
5. Dandan Zhang, Chunhong Shao, Minhua Shao, Pengrong Yan, Yi Wang, Yixiao Liu, Wenhong Liu, Tong Lin, Yuying Xie , Yingnan Zhao, Daru LuYifeng Li and Li Jin. Effect of μ-opioid Receptor Gene Polymorphisms on Heroin-induced Subjective Responses in a Chinese Population. Biol Psychiatry. 2007 61(11):1244-51.
 
6. *Yifeng Li, *Dandan Zhang, *Wei Jin, Chunhong Shao, Pengrong Yan, Yuying Xie, Daru Lu, Wei Huang, Li Jin.E487K Polymorphism of ALDH2 Is Responsible For Efficacy Variation of Sublingual Nitroglycerin in Chinese. Journal of Clinical Investigation. 2006 116(2): 506-11. (*equal contribution authors)
 
7. Rong Lin, Ying Wang, Yi Wang, Wenqing Fu, Dandan Zhang, Hongxiang Zheng, Ting Yu, Ying Wang, Min Shen, Rong Lei, Hong Wu, Aijun Sun, Ruifang Zhang, Xiaofeng Wang, Momiao Xiong, Wei Huang, Li Jin. Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population. Pharmacogenet Genomics. 2009 19(4):310-318.
 
8. Ling Xu, Fan Zhang, Dan-dan Zhang, Xing-dong Chen, Ming Lu, Ren-yong Lin, Hao Wen, Li Jin and Xiao-feng Wang. OPRM1 Gene Is Associated With BMI in Uyghur Population. Obesity (Silver Spring). 2009 17(1):121-5.
 
9. Yifeng Li, Chunhong Shao, Dandan Zhang, Pengrong Yan, Yuying Xie, Daru Lu, Li Jin. The Effect of Dopamine D2, D5 Receptor and Transporter (SLC6A3) polymorphisms on the Cue-Elicited Heroin Craving in Chinese. American Journal of Medical Genetics. 2006 141(3): 269-73.
 
10. Chunhong Shao, Yifeng Li, Kaida Jiang, Dandan Zhang,Yifeng XuLing Lin QiuyingWangMin Zhao Li Jin. Dopamine D4 receptor polymorphism modulates cue-elicited heroin craving in Chinese. Psychopharmacology (Berl). 2006 Jun; 186(2):185-90.
Abstract
D. Zhang, L. Cheng, C. Liu. Telomere length in brain and psychiatric disorders. 58th Annual Meeting of the American Society of Human Genetics. Philadelphia, PA, November 11-15, 2008. Abstract #1801
Dandan Zhang, Yudong Qian, Nirmala Akula, Elliot S. Gershon, Chunyu Liu.
CNV Detection From GWAS data: Comparison of Four Software Suites. XVII World Congress of Psychiatric Genetics, San Diego, SD, November 4-8, 2009, Abstract #127.
 
Dandan Zhang, Jinsong Tang, Lijun Cheng, Fabio Pibiri, Chao Chen, Chunling Zhang, Judith Badner, Elliot S. Gershon, Chunyu Liu. Rare CNVs Affect Gene Expression in Human Cerebellum. XVIII World Congress of Psychiatric Genetics, Athens, Greece, October 3-7, 2010.
 
Invited Talk
Genetic control of individual differences in gene-specific methylation in human brain.XVII World Congress of Psychiatric Genetics, San Diego, SD, November 4-8, 2009.
Research work

1)Copy number variation: Discovering the roles of copy number variations in complex diseases. 2) Genetics of complex diseases: Hunting for causal and susceptible genes underlining complex diseases by population-based and family-based strategies; identification of the functional effect of the genetic variants interested using molecular biology methods and animal models. 3) Epigenetics of complex diseases: Identification of DNA methylation changes in complex disease and dynamic DNA methylation changes over time. 4) Pharmacogeomics: To study how an individual's genetic inheritance affects the individual body's response to drugs, and further invention of more powerful medicines or new administration method, which will provide theoretic foundation to the individual therapy.

Contact

Phone:0571-88208138
E-mail:dandanz@zju.edu.cn